ResearchBiotechnology

Biomimetic Materials Laboratory

Group Leader
Mustafa O. Güler

Research Interest
Bioinspired and Biomimetic Materials, Functional Materials, Self-assembled Supramolecular Systems, Regenerative Medicine, Materials for Renewable Energy

Research Overview
Working at the boundary between biology, chemistry and materials science, Dr. Guler’s research group utilizes peptide and polymer networks to understand how the chemical structure alters biological function in both natural systems and nanotechnology-derived healthcare materials. Inspired by the great diversity of functional groups in biological systems, Dr. Guler’s group employs a vast variety of functional groups, such as bioactive amino acid sequences, metal-chelating motifs, steroid rings and glycosaminoglycan-mimicking elements, to design biocompatible, biodegradable and biofunctional materials, with emphasis on the use of peptide amphiphile gels in medical settings.

Nanobiotechnology Research Group

Group Leader
Ayşe B. Tekinay

Research Interest
Regenerative Medicine, Molecular Neuroscience, Genetic Manipulation of Organisms for Developing Sustainable Technologies

Research Overview
Dr. Tekinay’s group focuses on the enhancement of natural regenerative processes through the use of peptide amphiphile gels possessing functional groups similar to that found in the extracellular matrix. These peptide networks are capable of retaining growth factors and facilitating cell attachment and differentiation, thereby creating an environment conductive for regeneration to occur. Tekinay group also investigates drug delivery systems using a diverse array of nanocarriers, including nanofibers, liposomes and SPIONs.

Synthetic Biotechnology Laboratory

Group Leader
Urartu Şeker

Research Interest
Synthetic Biology, Genetically Engineered Organisms/Biodevices, Genetic Engineering and Protein Engineering at the Bio-Nano interface, Medical Biotechnology

Research Overview
The emerging field of synthetic biology allows the “programming” of simpler organisms, such as yeasts and bacteria, as one-cell laboratories for the detection of toxins and other health hazards, biological catalysts for a variety of reasons, or factories for the production of secondary metabolites that may be difficult to synthesize by conventional means. Dr. Şeker’s research group combines the synthetic potential of cellular programming methods with the unique properties of nanoscale materials to produce functional “bio-devices” for a variety of applications. Dr. Seker’s research group is also interested designing and implementation of bio-nano sensors and protein/peptide based nanomaterials.

Elbüken Research Group

Group Leader
Çağlar Elbüken

Research Interest
Microdroplet-based Microfluidic Systems, Integrated Microfluidic Systems

Research Overview
We are working on developing fundamental understanding and applications of fluid flow at small scale. We are specifically interested in control of biological liquids with extreme precision. Exquisite control of nanoliter size fluid packages enables high throughput studies using minute amounts of samples. Such systems address a broad range of applications. We explore applications in single cell studies.