EventsAssoc. Prof. Joao F. Mano

Nano-Multilayered Polymeric Assembled Systems in Hierarchical Devices for Biomedical Applications

Nanostructured multilayered films have been often fabricated using the layer-by-layer technology, where sequential layers of macromolecules are well stabilized by electrostatic interactions or other weak forces. Using adequate templates, non-flat coatings can be fabricated with tuned compositions along the build-up assembly. This enables the production of very well controlled multifunctional and structural devices using mild processing conditions that could be useful in biomedicine, including in tissue engineering or in drug delivery. In such applications, where there is a direct interaction between the implant with tissues and cells, the biomaterials must exhibit adequate surface characteristics, both at the chemical and topographic points of view. Examples of structures having nano-stratified multilayered organizations as building-blocks are presented, based on the use of natural or biomimetic macromolecules. Functional and bio-instructive multilayers may be produced by introducing special chemical groups or bioactive agents in the assembly. Such elements may be then hierarchically

About The Speaker

João F. Mano received his PhD in Chemistry in 1996 from the Technical University of Lisbon. Currently he is Associate Professor with habilitation at the Polymer Engineering Department, School of Engineering, University of Minho, Portugal, and he is a vice-director of the 3B’s research group, Biomaterials, Biodegradables and Biomimetics, which is a member of the ICVS/3B’s Associate Laboratory. His current research interests include the use of biomaterials and cells towards the development of transdisciplinary concepts for biomedical applications, especially aimed at being used in tissue engineering of bone and cartilage and in the controlled delivery of bioactive molecules. Dr. Mano has received different honours and awards: (i) fellow of the IUPAC (International Union of Pure and Applied Chemistry) since 2004; (ii) the Stimulus to Excellence Award by the Portuguese Minister for Science and Technology in 2005; (iii) the Materials Science and Technology Prize, attributed by the Federation of European Materials Societies (FEMS) in 2007 (iv) UNESCO Chair on Biomaterials attributed in 2008 from the University of Havana (Cuba); (v) the major BES innovation award in 2010 (at that time, one of the most recognised innovation prize in