The Nexus of Science and Translational Research: Lab-to-Market Applications of Tissue Engineering, Pharmaceutical Industry and Nanotechnology
This talk will discuss the fundamentals and translational applications of integrated microphysiological systems for various biomedical, pharmaceutical and nanomedicine research. Microphysiological platforms are consisted of interacting organ-on-chips and tissue-engineered 3D organ constructs that use human cells. An organ-on-chip, thereby, is a cell culture device composed with microchip manufacturing methods. Modeling sophisticated in vitro physiological responses under accurate conditions is an emerging technological field to engineer microchips containing living cells that reconstitute organ-level-functions for drug screening, diagnostics, toxicology and therapeutic purposes. In this context, in the first part of the talk, I will introduce different in vitro models including tumor vasculature interactions and smart delivery systems. Subsequently, in the second part, I will be describing how these platforms find lab-to-market applications with recent advances in translational research, commercialization endeavours and industrial partners that I have had. Lastly, I will present state-of-the-art research thrusts and vision of translational research for new discoveries.
About The Speaker
Dr. Gurkan Yesiloz received his Ph.D. degree in engineering from the University of Waterloo (Ontario, Canada) where he also had postdoctoral research. He has been involved the Velocity Program at the University of Waterloo which is a signature incubator program for startup expertise, tools and business advisory. Dr. Yesiloz is currently a Postdoctoral Associate at the University of Calgary (Alberta, Canada) and the CEO and Co-founder of DropTissue BioTech Inc. In the meanwhile, Dr. Yesiloz is also engaged in as Product Development Consultant and Research Scientist at Advanced Orthomolecular Research Inc. which is a drug delivery company in Canada. Dr. Yesiloz’s research interests lie in broad interdisciplinary studies, which intersect the engineering of biomedical devices/sensors, organ-on-chip platforms, tissue engineering, mechatronics systems, micro/nanofluidics, BioMEMS/NEMS and their applications in medicine, pharmaceutical and bio-engineering fields. He is recipient of several awards such as Jack Rosen Memorial Award for Environmental Innovation, NSERC-CMC Microsystems Microfabrication Award, Outstanding Teaching and International Doctoral Research Award from UWaterloo and First Rank Award of Engineering Faculty from Turkish Educational Foundation. His scientific studies are published in prestigious peer-reviewed journals and presented in international conferences.