Publications

2017

Cinar G, Ozdemir A, Hamsici S, Gunay G, Dana A, Tekinay AB, Guler MO. Local delivery of doxorubicin through supramolecular peptide amphiphile nanofiber gels, Biomaterials Science, 2017, doi: 10.1039/C6BM00656F.

2016

Sever M, Turkyilmaz M, Sevinc C, Cakir A, Ocalan B, Cansev M, Guler MO, Tekinay AB. Regenerative effects of peptide nanofibers in an experimental model of Parkinson’s disease, Acta Biomaterialia, 2016, doi: 10.1016/j.actbio.2016.09.011.

Mammadov M, Sever M, Gecer M, Zor F, Ozturk S, Akgun H, Ulas UH, Orhan Z, Guler MO, Tekinay AB. Sciatic nerve regeneration induced by glycosaminoglycan and laminin mimetic peptide nanofiber gels, RSC Advances, 2016, 6, 110535.

Ozkan AD, Tekinay AB, Guler MO, Tekin ED. Effects of temperature, pH and counterions on the stability of peptide amphiphile nanofiber structures, RSC Advances, 2016, 6, 104201-104214.

Hamsici S, Cinar G, Celebioglu A, Uyar T, Tekinay AB, Guler MO. Bioactive Peptide Functionalized Aligned Cyclodextrin Nanofibers for Neurite Outgrowth, Journal of Materials Chemistry B, 2016, doi: 10.1039/C6TB02441F.

Caliskan OS, Sardan Ekiz M, Tekinay AB, Guler MO. Spatial Organization of Functional Groups on Bioactive Supramolecular Glycopeptide Nanofibers for Differentiation of MSCs to Brown Adipogenesis, Bioconjugate Chemistry, 2016, doi: 10.1021/acs.bioconjchem.6b00632.

Senturk B, Cubuk MO, Ozmen MC, Aydin B, Guler MO, Tekinay AB. Inhibition of VEGF mediated corneal neovascularization by anti-angiogenic peptide nanofibers, Biomaterials, 2016, doi: 10.1016/j.biomaterials.2016.08.045.

Ozkan AD, Topal AE, Dâna A, Guler MO, Tekinay AB. Atomic force microscopy for the investigation of molecular and cellular behavior, Micron, 2016, doi: 10.1016/j.micron.2016.07.011.

Tansik G, Kilic E, Beter M, Demiralp B, Kiziltas Sendur G, Can N, Ozkan H, Ergul E, Guler MO, Tekinay AB. A glycosaminoglycan mimetic peptide nanofiber gel as an osteoinductive scaffold, Biomaterials Science, 2016, DOI: 10.1039/c6bm00179c.

Senturk B, Mercan S, Delibasi T, Guler MO, Tekinay AB. Angiogenic Peptide Nanofibers Improve Wound Healing in STZ-Induced Diabetic Rats, ACS Biomaterials Science and Engineering, 2016, 2, 1180.5.

Uzunalli G, Mammadov R, Yesildal F, Alhan D, Ozturk S, Ozgurtas T, Guler MO, Tekinay AB. Angiogenic Heparin-Mimetic Peptide Nanofiber Gel Improves Regenerative Healing of Acute Wounds, ACS Biomaterials Science and Engineering, 2016, DOI: 10.1021/acsbiomaterials.6b00165.

Gulseren G, Khalily MA, Tekinay AB, Guler MO, Catalytic Supramolecular Self-Assembled Peptide Nanostructures for Ester Hydrolysis, J. Mater. Chem. B, 2016, DOI: 10.1039/C6TB00795C.

Ozdemir A, Sardan Ekiz M, Dilli A, Guler MO, Tekinay AB. Amphiphilic peptide coated superparamagnetic iron oxide nanoparticles for in vivo MR tumor imaging, RSC Advances, 2016, 6, 45135.

Mumcuoglu D, Sardan Ekiz M, Gunay G, Tekinay T, Tekinay AB, Guler MO. Cellular Internalization of Therapeutic Oligonucleotides by Peptide Amphiphile Nanofibers and Nanospheres, ACS Applied Materials and Interfaces, 2016, DOI: 10.1021/acsami.6b01526.

Ustun Yaylaci S, Sen M, Bulut O, Arslan E, Guler MO, Tekinay AB. Chondrogenic Differentiation of Mesenchymal Stem Cells on Glycosaminoglycan-Mimetic Peptide Nanofibers, ACS Biomaterials Science and Engineering, 2016, 2, 871.

Arslan E, Guler MO, Tekinay AB. Glycosaminoglycan-mimetic signals direct the osteo/chondrogenic differentiation of mesenchymal stem cells in a three-dimensional peptide nanofiber extracellular matrix mimetic environment,  Biomacromolecules, 2016, 17, 1280.

Ustun Yaylaci S, Sardan Ekiz M, Arslan E, Can N, Kilic E, Ozkan H, Orujalipoor I, Ide S, Tekinay AB, Guler MO. Supramolecular GAG-like Self-Assembled Glycopeptide Nanofibers Induce Chondrogenesis and Cartilage Regeneration, Biomacromolecules, 2016, 17, 679.

2015

Yasa IC, Gunduz N., Kilinc M, Guler MO, Tekinay AB. Basal Lamina Mimetic Nanofibrous Peptide Networks for Skeletal Myogenesis, Scientific Reports, 2015; 5: 16460.

Mammadov R, Cinar G, Gunduz N, Goktas M, Kayhan H, Tohumeken S, Topal AE, Orujalipoor I, Delibasi T, Dana A, Ide S, Tekinay AB, Guler MO. Virus-like nanostructures for tuning immune response, Scientific Reports, 2015; 5: 16728.

Doldur-Balli F, Ozel MN, Gulsuner S, Tekinay AB, Ozcelik T, Konu O, Adams MM. Characterization of a novel zebrafish (Danio rerio) gene, wdr81, associated with cerebellar ataxia, mental retardation and dysequilibrium syndrome (CAMRQ), BMC Neuroscience 2015; 16 (1), 1

Gulseren G, Yasa IC, Ustahuseyin O, Tekin ED, Tekinay AB, Guler MO. Alkaline Phosphatase-Mimicking Peptide Nanofibers for Osteogenic Differentiation, Biomacromolecules 2015; 16, 2198−2208

Loo Y, Goktas M, Tekinay AB, Guler MO, Hauser CA, Mitraki A. Self-Assembled Proteins and Peptides as Scaffolds for Tissue Regeneration, Advanced Healthcare Materials 2015 Oct 13. doi: 10.1002/adhm.201500402

Khalily MA, Gulseren G, Tekinay AB, Guler MO. Biocompatible Supramolecular Catalytic One-Dimensional Nanofibers for Efficient Labeling of Live Cells, Bioconjugate Chem. 2015; 26 (12), 2371–2375

Uzunalli G, Tumtas Y, Delibasi T, Yasa O, Mercan S, Guler MO, Tekinay AB.   Improving pancreatic islet in vitro functionality and transplantation efficiency by using heparin mimetic peptide nanofiber gels, Acta Biomater. 2015; DOI: 10.1016/j.actbio.2015.04.032

Unal Gulsuner H, Ceylan H, Guler MO, Tekinay AB.  Multi-Domain Short Peptide Molecules for In situ Synthesis and Biofunctionalization of Gold Nanoparticles for Integrin-Targeted Cell Uptake, ACS Appl Mater Inferfaces. 2015; 7 (20):10677-83

Mumcuoglu D, Sardan M, Tekinay T, Guler MO, Tekinay AB. Oligonucleotide Delivery with Cell Surface Binding and Cell Penetrating Peptide Amphiphile Nanospheres, Mol Pharm. 2015; 12 (5), 1584–1591

Unal-Gulsuner H, Gulsuner S, Mercan FN, Onat OE, Walsh T, Shahin H, Leeb MK, Dogu O, Kansu T, Topaloglu H, Elibol B, Akbostancı C, King MC, Ozcelik T, Tekinay AB. Reply to Tzoulis et al.: Genetic and clinical heterogeneity of essential tremor, PNAS 2015; DOI: 10.1073/pnas.1503756112

Goktas M, Cinar G, Orujalipoor I, Ide S, Tekinay AB, Guler MO. Self-Assembled Peptide Amphiphile Nanofibers and PEG Composite Hydrogels as Tunable ECM Mimetic Microenvironment, Biomacromolecules 2015;16 (4), 1247–1258

Unal-Gulsuner H, Atalay-Gengec N, Kılınc M, Erbil HY, Tekinay AB. Osteoselection supported by phase separated polymer blend films, J Biomed Mater Res A 2015; 103(1): 154-161.

2014

Unal-Gulsuner H, Gulsuner S, Mercan FN, Onat OE, Walsh T, Shahin H, Leeb MK, Dogu O, Kansu T, Topaloglu H, Elibol B, Akbostancı C, King MC, Ozcelik T, Tekinay AB. Mitochondrial serine protease HTRA2 p.G399S in a kindred with essential tremor and Parkinson disease, PNAS 2014; 111(51): 18285-18290.

Uzunalli G, Soran Z, Erkal TS, Dagdas YS, Dinc E, Hondur AM, Bilgihan K, Aydin B, Guler MO, Tekinay AB. Bioactive self-assembled peptide nanofibers for corneal stroma regeneration, Acta Biomater 2014; 10(3): 1156-1166.

Sever M, Mammadov B, Guler MO, Tekinay AB. Tenascin-C Mimetic Peptide Nanofibers Direct Stem Cell Differentiation to Osteogenic Lineage, Biomacromolecules 2014; 15: 4480.

Estrada V, Tekinay A, Müller HW. Neural ECM mimetics, Prog Brain Res 2014; 214: 391-413.

Ceylan H, Kocabey S, Unal Gulsuner H, Balcik OS, Guler MO, Tekinay AB. Bone-like mineral nucleating peptide nanofibers induce differentiation of human mesenchymal stem cells into mature osteoblasts, Biomacromolecules 2014; 15(7): 2407-2418.

Aydın Tekdaş D, Garifullin R, Sentürk B, Zorlu Y, Gundogdu U, Atalar E, Tekinay AB, Chernonosov AA, Yerli Y, Dumoulin F, Guler MO, Ahsen V, Gürek AG. Design of a Gd-DOTA-Phthalocyanine Conjugate Combining MRI Contrast Imaging and Photosensitization Properties as a Potential Molecular Theranostic, Photochem Photobiol 2014; 90(6): 1376-1386.

Unal Gulsuner H, Atalay Gengec N, Kilinc M, Erbil HY, Tekinay AB., Osteoselection supported by phase separated polymer blend films, J Biomed Mater Res A., 2014 Mar 12. doi: 10.1002/jbm.a.35164.

Arslan E, Garip IC, Gulseren G, Tekinay AB, Guler MO., Bioactive Supramolecular Peptide Nanofibers for Regenerative Medicine, Adv Healthc Mater. 2014 Feb 25. doi: 10.1002/adhm.201300491.

Mammadov B, Guler MO, Tekinay AB., Extracellular Matrix Mimetic Peptide Scaffolds for Neural Stem Cell Culture and Differentiation, Methods Mol Biol. 2014 Feb 12.

2013

Gengec NA, Gulsuner HU, Erbil HY, Tekinay AB., Selective adsorption of L1210 leukemia cells/human leukocytes on micropatterned surfaces prepared from polystyrene/polypropylene-polyethylene blends, Colloids Surf B Biointerfaces. 2013 Sep 26;113C:403-411. doi: 10.1016/j.colsurfb.2013.09.040. [Epub ahead of print]

Kocabey, S., Ceylan, H., Tekinay, A.B., Guler, M.O., Glycosaminoglycan Mimetic Peptide Nanofibers Promote Mineralization by Osteogenic Cells, Acta Biomaterialia,2013, 2013, 9, 9075.

Ustun S, Kocabey S, Guler MO, Tekinay AB., Peptide nanofiber scaffolds for multipotent stromal cell culturing, Methods Mol Biol. 2013;1058:61-76. doi: 10.1007/7651_2012_5.

Mammadov, B., Sever,M., Guler, M.O., Tekinay, A.B., Neural differentiation on synthetic scaffold materials, Biomaterials Science, 2013,1, 1119-1137.

Ceylan, H., Ozgit-Akgun, C., Erkal, T.S., Donmez, I., Garifullin, R., Tekinay, A.B., Usta, H., Biyikli, N., Guler, M. O., Size-controlled conformal nanofabrication of biotemplated three-dimensional TiO2 and ZnO nanonetworks, Scientific Reports, 2013, 3, 2306, DOI: 10.1038/srep02306.

Ayas, S., Cinar, G., Ozkan, A.D., Soran, Z., Ekiz, O.O., Kocaay, D., Tomak, A., Toren, P., Kaya, Y., Tunc, I., Zareie, H., Tekinay, T., Tekinay, A.B., Guler, M.O., Dana, A., Label-Free Nanometer-Resolution Imaging of Biological Architectures through Surface Enhanced Raman Scattering, Scientific Reports, 2013, 3, 2624, DOI:10.038/srep02624.

Tekinay, A.B., Guler, M.O., Mumcuoglu, D., Ustun, S., Peptide nanofibers for controlled growth factor release, Therapeutic Delivery, 2013, 4, 651. (Invited Editorial Review)

Sardan, M., Kilinc, M., Genc, R., Tekinay, A.B., Guler, M. O., Cell Penetrating Peptide Amphiphile Integrated Liposomal Systems for Enhanced Delivery of Anticancer Drugs to Tumor Cells, Faraday Discussions, 2013, DOI: 10.1039/C3FD00058C.

Ustun S, Tombuloglu A, Guler MO, Tekinay AB, Growth and differentiation of pre-chondrogenic cells on bioactive self-assembled peptide nanofibers, Biomacromolecules, 2013, 14(1):17-26.

Huri E, Beyazit Y, Mammadov R, Toksoz S, Tekinay AB, Guler MO, Ustun H, Kekilli M, Dadali M, Celik T, Astarci M, Haznedaroglu IC (2013) Generation of Chimeric “ABS Nanohemostat” Complex and Comparing Its Histomorphological In Vivo Effects to the Traditional Ankaferd Hemostat in Controlled Experimental Partial Nephrectomy Model, Int J Biomater., 949460.

Mammadov R, Duman E, Guler MO, Tekinay AB, The Role of Heparin Mimetic Peptide Nanofibers in Angiogenesis Process, Book Chapter, Angiogenesis: insights from a systematic overview, NOVA Publishing Group, 2013, in print.

2012

Mammadov R, Mammadov B, Guler MO, Tekinay AB, Growth Factor Binding on Heparin Mimetic Peptide Nanofibers, Biomacromolecules, 13(10), 3311-3319, October 2012.

Ceylan H, Urel M, Erkal TS, Tekinay AB, Dana A, Guler MO, Mussel-Inspired Dynamic Crosslinking of Self-Healing Peptide Nanofiber Network, Advanced Functional Materials, 2012, DOI: 10.1002/adfm.201202291.

Tombuloglu A, Tekinay AB, Guler MO, Materials for Articular Cartilage Regeneration, Recent Patents Biomedical Engineering, 2012, 5, 187. (invited review)

Cinar G, Ceylan H, Urel M, Erkal TS, Deniz Tekin E, Tekinay AB, Dâna A, Guler MO, Amyloid Inspired Self-Assembled Peptide Nanofibers, Biomacromolecules, 13(10), 3377-3387, October 2012.

Mammadov B, Mammadov R, Guler MO, Tekinay AB, Cooperative Effect of Heparan Sulfate and Laminin Mimetic Peptide Nanofibers on Promotion of Neurite Outgrowth, Acta Biomaterialia, 8(6), 2077-2086, July 2012.

Ceylan H, Kocabey S, Tekinay AB, Guler MO, Surface-Adhesive and Osteogenic Self-Assembled Peptide Nanofibers for Bioinspired Functionalization of Titanium Surfaces, Soft Matter, 8, 3929, 2012.

Tombuloglu A, Akman A, Tekinay AB, Hücreler ve Organizmalar, Book Chapter, Moleküler Biyoloji, ISBN:6058801271, Ankara, Türkiye, Haziran 2012.

2011

Ceylan H, Tekinay AB, Guler MO, Selective Adhesion and Growth of Vascular Endothelial Cells on Bioactive Peptide Nanofiber Functionalized Stainless Steel Surface, Biomaterials, 32(34), 8797-8805, December 2011.

Bulut S, Erkal TS, Toksoz S, Tekinay AB, Tekinay T, Guler MO, Slow Release and Delivery of Antisense Oligonucleotide Drug by Self-Assembled Peptide Amphiphile Nanofibers, Biomacromolecules, 12(8): 3007–3014, 2011.

Mammadov R, Mammadov B, Toksoz S, Aydin B, Yagci R, Tekinay AB, Guler MO, Heparin Mimetic Peptide Nanofibers Promote Angiogenesis, Biomacromolecules,12 (10), 3508–3519, 2011.

Mammadov R, Tekinay AB, Dana A, Guler MO, Microscopic Characterization of Peptide Nanostructures, Micron, 43, 69, 2012.

Sulek S, Mammadov B, Mahcicek DI, Sozeri H, Atalar E, Tekinay AB, Guler MO, Peptide Functionalized Superparamagnetic Iron Oxide Nanoparticles as MRI Contrast Agents, Journal of Materials Chemistry, 21, 15157-15162, 2011.

Dagdas YS, Tombuloglu A, Tekinay AB, Dana A, Guler MO, Interfiber Interactions Alter Stiffness of Gels Formed by Supramolecular Self-Assembled Nanofibers, Soft Matter, 7, 3524-3532, 2011.

Gulsuner S, Tekinay AB, Doerschner K, Boyaci H, Bilguvar K, Unal H, Ors A, Onat OE, Atalar E, Basak AN, Topaloglu H, Kansu T, Tan M, Tan U, Gunel M, Ozcelik T, Homozygosity mapping and targeted genomic sequencing reveal the gene responsible for cerebellar hypoplasia and quadrupedal locomotion in a consanguineous kindred, Genome Research, 21: 1995-2003, 2011.

Toksoz S, Mammadov R, Tekinay AB, Guler MO, Electrostatic Effects on Self-Assembly Mechanism of Peptide Amphiphiles, Journal of Colloid and Interface Science,356(1): 131-137, 2011.

Dagdas YS, Necip Aslan M, Tekinay AB, Guler MO, Dâna A, Nanomechanical characterization by double-pass force-distance mapping, Nanotechnology, 22(29):295704, 2011.

2009-1999

Tekinay AB, Nong Y, Miwa JM, Lieberam I, Ibanez-Tallon I, Greengard P, Heintz N, A role for LYNX2 in anxiety-related behavior, Proc Natl Acad Sci, (PNAS) U S A. 106(11):4477-82, 2009.

Hruska M, Keefe J, Wert D, Tekinay AB, Hulce JJ, Ibañez-Tallon I, Nishi R, Prostate Stem Cell Antigen Is an Endogenous lynx1-Like Prototoxin That Antagonizes {alpha}7-Containing Nicotinic Receptors and Prevents Programmed Cell Death of Parasympathetic Neurons, Journal of Neuroscience, 29(47):14847-54, 2009.

Tekinay AB, Tekinay T, Ozcelik T.,Nanobiyoteknoloji, Book Chapter, Moleküler Parazitoloji, Türkiye Parazitoloji Derneği, Yayın No:22, ISBN 978-975-94646-9-1, Izmir, 2009.

Cayci C, Wahlquist BC, Seckin SI, Ozcan V, Tekinay AB, Martens TP, Oz MC, Ascherman JA, Naringenin inhibits neointimal hyperplasia following arterial reconstruction with interpositional vein graft, Annals of Plastic Surgery, 64(1):105-13, 2010 Jan.

Targeted disruption of lynx2 reveals distinct functions for lynx homologues in learning and behavior”, Tekinay, AB. 2006. PhD Dissertation, Rockefeller University

Ibanez-Tallon I, Wen H, Miwa JM, Xing J, Tekinay AB, Ono F, Brehm P, Heintz N, Tethering naturally occurring peptide toxins for cell-autonomous modulation of ion channels and receptors in vivo, Neuron, 43(3):305-11, 2004 Aug 5.

Gul A, Aslantas AB, Tekinay T, Konice M, Ozcelik T, Procoagulant mutations and venous thrombosis in Behcet’s disease, Rheumatology (Oxford), 38(12):1298-9, 1999 Dec.