MSN 519 Applications of Microfluidics and Nanofluidics
MSN 519 is offered every Fall term.
Micro/nanofluidics has emerged as an enabling field through joint efforts of researchers from different disciplines. The application of fluidic concepts to micro/nanosystems yielded lab-on-a-chip devices as a solution for several scientific challenges. Today, increasing demand to gather and process information at low-cost ranks lab-on-a-chip devices high priority for several applications.
The goal of this course to cover the fundamentals and the latest developments in the field of micro/nanofluidics and their application areas as lab-on-a-chip devices. This course will enable the students to familiarize themselves with the fundamental concepts of micro/nanofluidics and will help them to develop a thought process to evolve this understanding into functional analysis systems. By the completion of this course, the students will be able to follow the latest developments on lab-on-a-chip devices. There are no prerequisite courses.
Week 1: Characteristics of fluids: Let the mountains flow!
Week 2: Flow at small scale: Solving the $1,000,000 question
Week 3: The world of dimensionless numbers: Does exercise increase your expected life span?
Week 4: The art of precision: Blood (current) flow in electrical (cardiovascular) circuit (system)
Week 5: Particles inside flow: diffusion, settling, self-alignment – The beauty of symmetry/unification
Week 6: Materials, fabrication and components: The micro/nanofluidic toolbox
L1: Hands-on laboratory practice
L2: Hands-on laboratory practice
Week 7: Lab-on-a-Chip (LOC) devices – There is plenty of applications at the top
Week 8: Diagnostics & Point-of-care devices: How MSN 519 can save your life?
Week 9: Electrostatics & Electro-osmotic flow
Week 10: Electrophoresis & Dielectrophoresis: “Dialectical electrophoresis”
L3: Hands-on laboratory practice
Week 11: LOC devices for protein and nucleic acid analysis
Week 12: LOC for organ-on-a-chip studies
L4: Hands-on laboratory practice
Week 13: Commercialization of Lab-on-a-Chip systems
Week 14: Term project presentations
- Nam-Trung Nguyen, Steven T. Wereley, Fundamentals and Applications of Microfluidics, 2nd edition, 2006
- Bingcheng Lin, Microfluidics Technologies and Applications Topics in Current Chemistry, 2011
- Jean Berthier, Pascal Silberzan, Microfluidics for Biotechnology, 2nd edition, 2009
- Wei-Cheng Tian, Erin Finehout, Microfluidics for Biological Applications, 2009
- Patrick Abgrall, Nam-Trung Nguyen, Nanofluidics, 2009
Midterm exam 1: 15%
Midterm exam 2: 15%
Final Exam: 30%
Homework assignments: 15%
Term Project: 25%
Monday 13:40 (SU-01)
Wednesday 15:40 (SA-Z02)