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X-ORIGINAL-URL:https://unam.bilkent.edu.tr
X-WR-CALDESC:UNAM Nanoteknoloji Araştırma Merkezi için etkinlikler
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DTSTART:20260101T000000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Moscow:20260401T110000
DTEND;TZID=Europe/Moscow:20260401T123000
DTSTAMP:20260917T014646
CREATED:20260325T111436Z
LAST-MODIFIED:20260325T111436Z
UID:11552-1775041200-1775046600@unam.bilkent.edu.tr
SUMMARY:From Molecules to Populations: How Single-Cell Stochasticity Drives Population Heterogeneity in Bacteria
DESCRIPTION:Murat Tuğrul\nHumboldt-Universität zu Berlin \n\nA central challenge in evolutionary biology is predicting how microscopic processes within a cell determine the macroscopic success of a population. While classical population genetics often treats cellular fitness as a scalar parameter\, real biological populations are characterized by profound phenotypic heterogeneity\, even among genetically identical individuals. In this talk\, I will present a multiscale framework that links biophysical mechanisms directly to population-level outcomes and heterogeneity. First\, I will show single-cell microscopy techniques that allow us to collect high-resolution data on physiological states\, gene expression\, and fitness components in bacteria. Integrating mathematical modeling with single-cell experiments\, I will demonstrate how stochastic damage dynamics and asymmetric segregation reshape individual lifespans and emergent population growth. Second\, I will focus on the complex regulatory systems controlling polygenic traits\, specifically the flagellar network. I will show how the biophysical logic of genetic networks generates phenotypic bimodality\, providing a strategic ‘hedge’ that might facilitate evolutionary survival. Finally\, I will argue for a transition toward a mechanistic evolutionary theory where the physics of the cell dictates the logic of adaptation\, offering new insights into global challenges such as antibiotic resistance. \n \n  \nKonuşmacı hakkında\nDr. Murat Tuğrul is a biophysicist and theoretical evolutionary biologist studying how stochastic processes at the single-cell level give rise to population-level heterogeneity and evolution. He is currently a Research Fellow in the Molecular Microbiology Lab at Humboldt-Universität zu Berlin\, where he combines mathematical modeling with single-cell data analysis to investigate the regulatory principles of bacterial flagellar systems. Previously\, he led a Marie Skłodowska-Curie project at Freie Universität Berlin focused on bacterial aging and damage accumulation in single cells. He completed his PhD at IST Austria\, developing biophysical and population genetic models of transcriptional evolution. His research integrates theory and experiment to build predictive\, multiscale frameworks for understanding how cellular processes shape fitness and evolution in microbial populations. \n \n 
URL:https://unam.bilkent.edu.tr/etkinlikler/from-molecules-to-populations-how-single-cell-stochasticity-drives-population-heterogeneity-in-bacteria/
CATEGORIES:Nanokolokyumlar
ATTACH;FMTTYPE=image/jpeg:https://unam.bilkent.edu.tr/tr/wp-content/uploads/2026/03/Murat-Tugrul.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Moscow:20260415T110000
DTEND;TZID=Europe/Moscow:20260415T123000
DTSTAMP:20260917T014646
CREATED:20260406T123953Z
LAST-MODIFIED:20260407T051240Z
UID:11586-1776250800-1776256200@unam.bilkent.edu.tr
SUMMARY:Building a minimal nucleus to understand structure and  mechanics of assembly
DESCRIPTION:Alexander Von Appen\nMPI of Molecular Cell Biology and Genetics \n\nThe nucleus\, the largest organelle in human cells\, plays a crucial role in protecting\, organizing\, and regulating our genome. Despite its complexity\, it undergoes remarkable dynamics during cell division: as the cell enters mitosis\, nuclear organization dissolves\, leading to the detachment of the nuclear membrane from chromatin. The nucleoplasm and cytoplasm merge into a single entity\, while the spindle distributes chromosomes to form daughter cells. Following this “open” mitosis\, the entire organelle reassembles within minutes\, prompting the central question: what molecular mechanisms drive nuclear self-assembly? \nI will present our latest efforts to reconstitute nuclear self-assembly processes\, which we study structurally using cryo-electron tomography and mechanically using optical tweezers. Specifically\, I will show how ESCRT proteins assemble to close the nuclear membrane and how DNA is organized at the chromatin–nuclear membrane interface. \n \n  \n  \nKonuşmacı hakkında\nPhD\, EMBL Heidelberg\, with Martin Beck\, studying the structure of the human nuclear pore complex PostDoc\, UCSF San Francisco\, with Adam Frost\, studying the role of phase separation in ESCRT-mediated nuclear membrane assembly Since 2021\, Research Group Leader at the Max Planck Institute of Molecular Cell Biology and Genetics\, Dresden\, Germany \n \n 
URL:https://unam.bilkent.edu.tr/etkinlikler/building-a-minimal-nucleus-to-understand-structure-and-mechanics-of-assembly/
CATEGORIES:Nanokolokyumlar
ATTACH;FMTTYPE=image/jpeg:https://unam.bilkent.edu.tr/tr/wp-content/uploads/2026/04/Von-Appen.jpg
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BEGIN:VEVENT
DTSTART;TZID=Europe/Moscow:20260417T090000
DTEND;TZID=Europe/Moscow:20260417T170000
DTSTAMP:20260917T014646
CREATED:20260401T105837Z
LAST-MODIFIED:20260401T121434Z
UID:11565-1776416400-1776445200@unam.bilkent.edu.tr
SUMMARY:ZEISS ve UNAM’dan Semiconductor Advances Summit’26
DESCRIPTION:Bilkent Üniversitesi Ulusal Nanoteknoloji Araştırma Merkezi (UNAM) ve ZEISS iş birliğiyle düzenlenen Semiconductor Advances Summit’26 etkinliği\, 17 Nisan 2026 Cuma günü Ankara’daki ZEISS Müşteri Merkezi’nde gerçekleştirilecektir. Yarı iletken bilimi ve mühendisliğinin geleceğini şekillendiren güncel gelişmelerin ele alınacağı etkinlik\, önde gelen araştırmacılar ile sektör uzmanlarını bir araya getirmeyi amaçlamaktadır. \nUNAM İcra Kurulu Başkanı Prof. Dr. Hilmi Volkan Demir\, “Yarı İletken Nanokristal Kuantum Optoelektroniği: Dalga Fonksiyonu Mühendisliğinden Kuantum Saflığına” başlıklı konuşmasıyla yarı iletken nanokristaller ve kuantum optoelektronik alanındaki güncel araştırmalarını ve yenilikçi yaklaşımlarını paylaşacaktır. Zirvede ayrıca ZEISS İş Geliştirme Müdürü Gabriel Reichl\, Singapur Ulusal Üniversitesi Malzeme Bilimi ve Mühendisliği Bölümü Öğretim Üyesi Doç. Dr. Mario Lanza Martinez\, TÜBİTAK’tan Ahmet Çeliktaş\, Türkiye Entegre Devreler İttifakı (TICA) temsilcisi Elif Tepeli ve ZEISS Kıdemli Uzman Kasem Bau da konuşmalarıyla yer alacaktır. \nSemiconductor Advances Summit’26\, akademi ve endüstri arasında iş birliği ve etkileşim için dinamik bir platform oluştururken\, katılımcılara kuantum optoelektronik\, Moore sonrası elektronik malzeme ve cihazlar\, entegre devre ekosistemleri ile ileri karakterizasyon ve arıza analizi teknikleri başta olmak üzere bütüncül bir perspektifle zengin bir içerik sunacaktır. \nKayıt olmak için \n 
URL:https://unam.bilkent.edu.tr/etkinlikler/zeiss-ve-unamdan-semiconductor-advances-summit26/
CATEGORIES:UNAM Etkinlikler
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BEGIN:VEVENT
DTSTART;TZID=Europe/Moscow:20260429T110000
DTEND;TZID=Europe/Moscow:20260429T123000
DTSTAMP:20260917T014646
CREATED:20260421T065133Z
LAST-MODIFIED:20260421T101531Z
UID:11640-1777460400-1777465800@unam.bilkent.edu.tr
SUMMARY:Injectable Cryogels for Biomedical Applications:  from Tissue Engineering to Immunotherapy
DESCRIPTION:Sidi A. Bencherif\nUniversity of Rouen Normandy\nNortheastern University \n\nAcross cell therapy\, regenerative medicine\, and immunoengineering\, there is a need for advanced three-dimensional (3D) scaffolds that support cells\, modulate their behavior\, and guide tissue regeneration. Injectable biomaterials have become especially attractive\, offering minimally invasive delivery without the risks of open surgery while enabling precise placement within delicate tissues. In this context\, we introduced a breakthrough platform: large\, preformed macroporous cryogels that can be delivered through a standard needle–syringe system while preserving their structure and function [1]. Our 2012 report of the first injectable cryogel capable of passing through a hypodermic needle while maintaining native-like microenvironmental cues sparked widespread interest and helped redefine the design space of soft biomaterials [2]. These sponge-like constructs\, produced through environmentally friendly cryogelation\, exhibit unique features—including elasticity\, interconnected macroporosity\, and shape-memory behavior enabling complete geometric recovery after injection. Over the past decade\, injectable cryogels have emerged as a versatile and customizable class of biomaterials aligned with modern research priorities. They hold great promise for tissue repair\, controlled drug delivery\, cell therapies\, cancer immunotherapy\, and innovative vaccine platforms\, including those developed during the COVID-19 era [3–5]. \nAcknowledgements\nFinancial support from the Chaire d’Excellence de Normandie is gratefully acknowledged. \nReferences\n[1] L.J. Egremont et al. Trends in Biotechnology 2019\, 38:418–431.\n[2] S.A. Bencherif et al. PNAS 2012\, 109\, 19590–19595.\n[3] M. Rezaeeyazdi et al. Materials Today Bio 2022\, 100207.\n[4] S.A. Bencherif et al. Nature Communications 2015\, 6:7556.\n[5] T. Colombani et al. Advanced Science 2021\, 2100316. \n \n  \n  \nKonuşmacı hakkında\nSidi A. Bencherif\, Ph.D.\, is a senior researcher at the French National Centre for Scientific Research (CNRS) and a faculty-affiliated principal investigator at the University of Rouen Normandy. He earned his Ph.D. in Chemistry from Carnegie Mellon University and completed his postdoctoral training at Harvard University. His research focuses on the design and development of advanced biomaterials—particularly injectable and macroporous cryogels—for applications in regenerative medicine\, controlled drug delivery\, and cancer immunotherapy. His work bridges fundamental materials science with translational biomedical applications. Dr. Bencherif has authored over 100 peer-reviewed publications in leading journals\, including Science\, Nature Materials\, Nature Communications\, PNAS\, Advanced Science\, Bioactive Materials\, Cell Biomaterials. His work has received ~15\,000 citations (h-index: 51)\, and he is an inventor on 15 patents. He has been recognized among the world’s top 2% of most-cited scientists (Stanford/Elsevier) and has received numerous prestigious honors\, including the U.S. NSF CAREER Award\, ACS PMSE Young Investigator Award\, ACS I&EC Influential Researcher Award\, BMES-CMBE Rising Star Award\, and more recently the Normandy “Chair of Excellence.” \n \n 
URL:https://unam.bilkent.edu.tr/etkinlikler/injectable-cryogels-for-biomedical-applications-from-tissue-engineering-to-immunotherapy/
CATEGORIES:Nanokolokyumlar
ATTACH;FMTTYPE=image/jpeg:https://unam.bilkent.edu.tr/tr/wp-content/uploads/2026/04/Sidi-A.-Bencherif.jpg
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