Effect of surface charged groups on colloidal, optical properties and cellular uptake of inorganic nanoparticles

Mikhail Artemyev

Belarusian State University

Effect of surface charged groups on colloidal, optical properties and cellular uptake of inorganic nanoparticles

Surface charged groups play enormous role in colloidal stabilization of inorganic nanoparticles in aqueous solutions. They also govern such important characteristics, as electrophoretic mobility, ability to electrostatic interaction with different objects from solid surfaces to biomolecules. Here, I present our recent results on how to introduce different types of charged groups in the surface shell of semiconductor and metal nanoparticles, how the sign and the magnitude of the surface charge and the type of groups affect colloidal stability of nanoparticles in aqueous media. Surprisingly, the surface charge affects not only their electrophoretic mobility, but indirectly their hydrodynamic size measured by DLS. Both strong negative and positive surface charge is capable to quench the photoluminescence of semiconductor quantum dots and cause a spectral shift of plasmon resonances in silver nanoparticles. Moreover, various types of cells demonstrate selective uptake of colloidal quantum dots with specific surface charge. All of that demonstrates practical perspectives for utilization of charged plasmonic and semiconductor nanoparticles as the optical nano-sensors and markers.

About Speaker

Graduated chemistry department of BSU in 1985. Defended Ph.D. in physical chemistry in 1991, in 2009 defended Dr.Sci. thesis. From 1985 up to now is an employee of RIPCP, from 2010 head of laboratory of nanochemistry. The main scientific activities lie in the synthesis of colloidal semiconductor and metal nanoparticles, investigating their optical properties, photochemical and electrochemical behavior, interaction with biomolecules and cells. Published more than 200 scientific papers, IF =45.